Evaluation of the Status of Prophylactic Administration of Antibiotics in Surgery Department of Shahid Sadoughi Hospital of Yazd City in 2018

Introduction: surgical site infection is one of the most important causes of mortality and morbidity: use of the prophylactic antibiotic is one of the effective methods for its prevention, the present study aimed to investigate the status of prophylactic administration of antibiotics in Surgery Department of Shahid Sadoughi Hospital of Yazd City in 2018. Methods: this descriptive cross-sectional study was performed on 600 patients from General Surgery Department of Shahid Sadoughi Hospital of Yazd City in 2018. Data were collected by questionnaire. Selection of the prophylactic antibiotic (pa), the dosage, time, type and the route of antibiotic administration were compared with ASHP ( American Society of Health System Pharmacistis) and -Clinical Medicine Strategy of Using Preventive Antibiotics in Surgeries (Iranian guideline). Data were analyzed by SPSS version 16 software. Results: Mean age of the patients was 35.02 ±19.12 years. Regarding the use or non-use of antibiotics 85.2%, the route of administration 85.2%, the dose of the drug 64.7% were in accordance with the instructions. The time of drug prescription was in accordance with the national instructions in 72.3% of cases and in accordance with ASHP in 72.8% of cases. The most inconsistency with ASHP and Iranian guideline was seen in the type of the antibiotic that was in accordance with ASHP and Iranian guideline in 50.7% and 48.8%, respectively. The overall appropriateness of PA was found in 50.7% and 48.8%  cases according to ASHP and Iranian guideline, respectively.   Conclusion: In the recent study, the most inconsistency with ASHP and Iranian guideline was seen in the type of prescription antibiotic.